Om os:
A peptide is a chain of amino acids linked by peptide bonds. Peptides are mainly involved in protein regulation, angiogenesis, cell proliferation, melanogenesis, cell migration, and inflammation. Bioactive peptides have been widely used in the cosmetic industry in recent decades. Peptides require low molecular weight (> 500 Da), in order to reduce the diffusion of the peptide between the epidermal layers, high stability and solubility. Over the years, the scientific community has developed a small and stable synthetic peptide fragment that activates collagen production and reduces facial wrinkles and pigmentation. Trifluoroacetyl tripeptide-2 (sequence: TFA-Val-Try-Val-OH) tripeptide synthesis, designed as a matrix metalloproteinase and elastase inhibitor. In vitro studies on the protection of ECM by trifluoro-acetyl tripeptide 2(TT2), the synthesis of proteoglycan in cell-matrix interactions, and the effect on progerin synthesis in mature human normal fibroblasts have been recently identified as a co-inducer of cellular senescence. The results suggest that trifluoroacetyl tripeptide 2 has a broader range of anti-aging properties. This reduces progerin synthesis, increases proteoglycan production, and shrinks collagen, thereby reducing wrinkles and improving tissue stiffness. In addition, its anti-wrinkling, anti-flow hanging and skin tightening effects were evaluated in two in vitro split face studies. Trifluoroacetyl tripeptide 2 has been shown to have progressive effects on wrinkles, tightness, elasticity, and sagging.
Kan trifluoroacetyltripeptid-2 forsinkelse aldring?
Undersøgelser har vist, at celle senescens er tæt knyttet til progerin. Med aldring akkumuleres Presenilin mere og mere i kroppen, hvilket fører til nukleare defekter og DNA -skade, hvilket fører til en række hud aldring. Trifluoroacetyltripeptid-2 er et aktivt tripeptid af Elafin, et derivat af elastaseinhibitor. Det reducerer progerinsyntese og forbedrer hudlaksitet, sagging og rynker.
Mekanisme
1. hæmmer syntesen af progerin for at forsinke cellulær senescens.
2. Fremme syndecan -produktion og forlænger cellelivet.
3. hæmmer aktiviteten af matrixmetalloproteinaser MMP1, MMP3 og MMP9, reducerer nedbrydningen af ekstracellulære matrixproteiner og opretholder deres integritet.
4. hæmmer elastaseaktivitet, reducer elastinnedbrydning og gør huden strammere og mere elastisk.
Anvendelse
Det er velegnet til alle slags anti-rynke og anti-aldring, opstramning, anti-fotoaging, post-fødsel og efter-sol-kropspleje osv. Det tilføjes i den sidste fase af kosmetikproduktion
Posttid: 2025-07-02